Profilin is required for viral morphogenesis, syncytium formation, and cell-specific stress fiber induction by respiratory syncytial virus
Abstract Background Actin is required for the gene expression and morphogenesis of respiratory syncytial virus (RSV), a clinically important Pneumovirus of the Paramyxoviridae family.In HEp-2 cells, RSV infection also induces actin stress fibers, which may be important in the immunopathology of the RSV disease.Profilin, a major regulator of actin p